Science Forward Fall 2017

Dr. Edyta Greer, Macaulay Honors College, Fall 2017

Author: Deanna Pisacreta

Blog Post 3 – Deanna Pisacreta

As someone who does not typically enjoy science courses, I found this class far surpassed my expectations. Dr. Greer presented the science in a way that it was accessible for the science impaired such as myself. The labs were a great learning experience, while also being somewhat simplistic in nature and fun.

I loved the 3D printing aspect of the course, and found that it was technology Baruch has that I otherwise would not have taken advantage of. I found that the 3D printing also put us a step above the other posters presented at the STEAM Festival. The other posters were very research and data heavy, but our classes were far more creative and innovative. I loved that we were able to show our own ideas at the festival, rather than simply presenting research conducted by other scientists.

Overall, I enjoyed this course far more than I ever expected to, and I am so grateful I chose to take Dr. Greer this semester!

Final – e.Patch Poster

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Blog Post 2 – Deanna Pisacreta

I think it is important to be doing a lab in a classroom setting to see what we have learned in a hands-on environment. A controlled lab environment with expected results is optimal for teaching purposes because it gives students a chance to learn how to complete an experiment with the correct methods and procedures. This way, those students learn how to correctly conduct an experiment if they chose to conduct one with unknown results in the future. In the context of “non-specialist” science courses, I think these labs are still a necessity. This is because a student in any science course should have the opportunity to conduct lab work, as it is an essential part of any of the sciences. In the labs for this class, I hope to gain the experience of hands-on science. I have learned the theory in class, and I’m excited to see the chemical reactions I’ve learned about happen before my eyes.

In a non-science course, such as history or American literature, a “lab” would look like any hands-on experience. For example, in a literature course a “lab” would be creating your own stories rather than just reading other authors. However, for a science lab report, a much different style of academic writing in necessary. It must be much dryer writing, in order to avoid personal opinions clouding the results. A lab report must be as unbiased as possible, it strips away all of the fluff writing in order to allow the data to speak for itself.

Poster Draft – Deanna Pisacreta, Joseph Gofman, Alvin Kissoon

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Medicated Patches – Annotated Bibliography

Popular Article:

Silver, Larry, M.D. “A Parent’s Guide to the Daytrana Patch.” ADDitude. August 03, 2017. Accessed October 22, 2017. https://www.additudemag.com/a-parents-guide-to-the-daytrana-patch/.

This article takes about a patch that is applied to the skin, stays on all day, and delivers medication for ADHA in increments throughout the day. This has been done before with non-prescription different medications such as ibuprofin. However, it has not been done with a drug of this nature before. This patch helps children, who often have difficulty swallowing pills, get the medication they desperately need. With something like this possible, it is not that far off to think that a patch similar to this, that delivers insulin to diabetics can be accomplished.

Peer Reviewed Sources:

Ali, Fatima Ramzan et al. 2017. “Design, Development, and Optimization of Dexibuprofen Microemulsion Based Transdermal Reservoir Patches for Controlled Drug Delivery.” https://www.hindawi.com/journals/bmri/2017/4654958/

This study speaks to the benefits and complications associated with transdermal drug delivery, specifically with ibuprofen. It talks about why transdermal delivery is effective, and how it works. They also mention that it is a method that is becoming increasingly popular, because in some cases people have difficulty swallowing large pills. Some of the complications include the skin’s natural chemical barriers that sometimes make it difficult for the drugs to get through to the bloodstream.

 

Moffatt, Kurtis, Yujing Wang, Thakur Raghu Raj Singh, and Ryan F Donnelly. 2017. “Microneedles for enhanced transdermal and intraocular drug delivery.” Current Opinion In Pharmacology 36, 14-21. MEDLINE Complete, EBSCOhost (accessed October 22, 2017). http://www.sciencedirect.com/science/article/pii/S1471489217300826?via%3Dihub

In this study they experimented with using microneedles in transdermal patches. In doing this they eliminate some of the complications with some patches not being able to deliver an effective drug through the skin’s chemical barriers. These patches can be applied easily by a patient, and are effective almost immediately. Patches like this, that use microneedles, are not currently available on the market, but the studies being done on them are very promising so far. If this same delivery method can be used for insulin delivery diabetics will be able to get the medication they need much easier, and those who are unable to inject themselves with their insulin dosages will no longer need help getting the medication they need.

Allium Sativum

 

Allium Sativum, commonly known as garlic, is an extremely popular household item. Most often used when cooking., Garlic contains at least 33 sulfur compounds and 17 amino acids. The sulfur compound responsible for garlic’s distinctive smell is allyl methyl sulfide (AMS).

 

Presentation 

 

Poster Idea – Lightweight Casts

Today, if you break a bone such as your arm, your doctor will most likely have you wear a plaster cast. Doctors around the world use plaster casts because of their durability, however that are not without their faults. This cast is be heavy, uncomfortable, and not waterproof so simple tasks such as showering become difficult and tedious. I have an idea to use 3D printing to create a lighter, more comfortable cast with the same durability as the plaster. This new version will lead to an overall more comfortable and easier healing process.

Deanna Pisacreta – Blog Post 1

I found throughout this article, there was more scientifically technical information than would be found in a New York Times article today. The way it was written, the intended audience has at least some science background. Early in the article, there was a bit more jargon than I was comfortable with, or I felt was appropriate for an article intended for the general public, but as I read further it became a much easier read.

I felt the molecular drawings, while interesting to look at, were unnecessary in a New York Times article. The publication is intended for a general audience, most of whom would not understand the visual representation of a molecule.

The study discussed in the article was quite interesting, and seems to be the beginning studies of modern day Plan B contraceptives. I am very curious to know if the drug discussed in this article is the same one that is a popular contraceptive today, or if this study was more of a starting point for other pharmaceutical companies to begin their own oral contraceptive research.

Overall, I felt had this study been done today, this same article in the New York Time would have been much shorter, and held much less hard fact. It would be much more opinionated, and contained less jargon to make it more accessible to the general public.

Paraphrase Exercise

It is the responsibility of school nurses to respond appropriately when a child suffers an allergic reaction from an unknown allergen. Unfortunately, conflicting policies between health care providers and the school district may cause confusion and therefore increase the child’s risk of anaphylaxis. Increasing the use of epinephrine as a treatment in schools has the potential to decrease that risk, and ensure the children’s safety while in school.

(Wahl et al. 2015, 97)

Is Coffee Bad for Your Bones?

Popular Article:

Is Coffee Bad for Your Bones?

Louis, Catherine Saint. 2017. “Is Coffee Bad for Your Bones?” The New York Times, (August 25). Accessed September 05, 2017.

 

Primary Literature:

Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children 

Wikoff, D., et al. 2017. “Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children”. Journal of Food and Chemical Toxicology, no. 102, (April): 1-64 http://dx.doi.org/10.1016/j.fct.2017.04.002

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