MHC Seminar 3, Professor Maya Weltman-Fahs, City College

Category: Week 2 (Page 2 of 2)

Assignment 2 – Tayba Aziz

Jolanta Airey, Frank R. Albano, Daphne C. Sawlwin, Alison Graves Jones, Neil Formica, Vince Matassa, Jane Leong, “Immunogenicity and safety of a quadrivalent inactivated influenza virus vaccine compared with a comparator quadrivalent inactivated influenza vaccine in a pediatric population: A phase 3, randomized noninferiority study”. Vaccine. Volume 35, Issue 20, 2017, Pages 2745-2752, ISSN 0264-410X, http://dx.doi.org/10.1016/j.vaccine.2017.03.028.

The purpose of this article was to address the safety of the inactivated influenza virus vaccine (Seqirus/CSL IIV3). Fevers in children were reported after having received the vaccination; because of this a new strain of the vaccination (IIV4) was tested to determine if the resulting fevers were a side effect of the new vaccination.

The researchers conducted the study in 32 centers across the United States. 2278 children were involved in the study with a ratio of 3:1 receiving the IIV4 or the comparator IIV4. The children were stratified by age into groups consisting of the age group 5-8 and 9-17. In the 5-8 age group severe fever was reported for 1.2% in the IIV4 and for comparator IIV4 it was reported for 0.7%. In the 9-17% severe fever was reported for 0.5% in the IIV4 group and no severe fever was reported for the comparator IIV4 group.

The results for this study showed that the effects of each were similar in both groups and well tolerated for both age groups. Most of the side effects that arose were mild and were resolved within a few days. This study proved that the IIV4 is more favorable and safe to use in younger children.

Assignment 2 – Katherine Johnson

Flueckiger, L., Lieb, R., Meyer, A. H., & Mata, J. (2014). How Health Behaviors Relate to Academic Performance via Affect: An Intensive Longitudinal Study. Plos ONE, 9(10), 1-10. doi:10.1371/journal.pone.0111080

This study aimed to determine the effects that sleep and physical activity had on students’ academic performance during an examination period. They carried out the study by having 72 first-year students answer online questionnaires on their sleep quality, physical activity, positive and negative affect, learning goal achievement, and examination grades on 32 consecutive days. The data were then analyzed using multilevel structural equation models.

Over the examination period, better average sleep quality but not physical activity predicted better learning goal achievement. Better learning goal achievement was associated with increased probability of passing all examinations. In terms of day-to-day dynamics, on days with better sleep quality, participants reported better learning goal achievement. Day-to-day physical activity was not related to daily learning goal achievement.

Assignment 2

P. D. Darbre, A Aljarrah, W. R. Miller, N. G. Coldham, M. J. Sauer and G. S. Pope. “Concentrations of Parabens in Human Breast Tumours.” Journal of Applied Toxicology, vol. 24, 2004, pp. 5–13.

NOT A FREE ARTICLE AND NOT ACCESSIBLE BY CCNY DATABASE so I have provided the link: http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.511.731&rep=rep1&type=pdf

Our research question was in search of whether ingredients within high end and drugstore foundations were any different from one another and whether one as a opposed to the other could clog pores or affect the health of the skin due to the differences in ingredients.

I found that in our high end sample of foundation (Giorgio Armani Luminous Silk Foundation retailing at $66) there were indeed parabens of some form specifically methylparaben and butylparaben (to be cautious of). And here my team and I thought with the higher price for the product, there would be less harmful ingredients.

My article concerned the relationship between parabens and breast tumours.

Breast tumor material was collected and stored in liquid nitrogen. After homogenizing, adding supernatant, centrifuging, etc, parabens were extracted from the tissue and analyzed by paper chromatography.

Results showed that parabens were indeed in the breast tissue. In four of the twenty tumors, there was more than the average level of paraben found. There were more parabens found than others which was mainly due to the fact it is more widely consumed. Considering the parabens found in the Armani foundation, it is quite possible for one who uses such a product regularly that it may be found in high concentrations in that person’s breast tissue.

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