The scientific experiment that I investigated involved using creatine as a treatment for Huntington’s Disease. The study lasted from 2009 to 2014 after 553 participants showing early signs of Huntington’s had volunteered. The study involved separating the participants into a group of 275 participants who would receive creative and a group of 278 who acted as the placebo group. The experimental group received increasing dosages of creatine from 10g to 40g. The results were exactly opposite of what the researchers had hypothesized and hoped for. The group that received creatine showed more adverse effects (not related to Huntington’s) and no improvement of their Huntington’s symptoms. Another major issue that came out of this study was he large dropout rate. The adverse affects caused by the creatine led to a dropout rate of 35 percent in the experimental group, and the lack of adverse affects of the placebo group led them to know they were in a placebo group and 26 percent dropped out. Because of this the experiment was prematurely cancelled.

 

 

“Latest Findings From CREST-E Trial Don’t Support Using the Dietary Supplement Creatine To Treat Huntington’s Disease.” National Center for Complementary and Integrative Health, U.S. Department of Health and Human Services, 14 July 2017, nccih.nih.gov/research/results/spotlight/crest-e-huntington. Accessed 15 Sept. 2017.