Throughout schools across the United States, nurses have been struggling to deal with the disparities within the guidelines from the school district and the American Academy of Asthma, Allergy and Immunology when administering epinephrine to students. Both institutions have different and extremely strict guidelines that leave nurses in a tough decision. This toss-up risks anaphylaxis if the administration is delayed. Studies have shown that the reactions that come with under treatment of epinephrine is a big safety concern (Boyce et al., 2010; Carlisle et a., 2010; Fleischer et al., 2012; Nowak-Wegrzyn, 2012b). Student nurses must then find the similarities and work around the guidelines in order to perform a safe and timely administration of epinephrine to their students (Wahl et al. 2015, 97).